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APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos

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Pyruvate dehydrogenase complex: metabolic link to ischemic brain injury and target of oxidative stress

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[DOI] [PubMed] [Google Scholar] Vali S, Mythri RB, Jagatha B, Padiadpu J, Ramanujan KS, Andersen JK, Gorin F, Bharath MM

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Intestinal barrier dysfunction results from food poisoning, dietary factors, and dysbiosis, and increased permeability leads to the translocation of sterile toxins and living or dormant microbes and lipopolysaccharides (LPS) into the bloodstream (de Punder and Pruimboom, 2013

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2.2.3 Other GM metabolites influence AMD development Organic fatty acids with a carbon chain length of less than six, known as short-chain fatty acids (SCFAs), are generated by bacteria in the gut, including 41 families, such as Lactobacillaceae , Clostridiaceae , Christensenellaceae Bifidobacteriaceae , Lachnospiraceae , and Akkermansia muciniphila

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The protective effect of uric acid in reducing TLR4/NF-B activation through the inhibition of HMGB1 acetylation in a model of ischemia-reperfusion injury in vitro

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