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The sustained-release drug delivery facilitated by microneedle systems can streamline drug administration, achieve therapeutic concentrations within a specified time frame, and minimize potential systemic toxicity [185]

doi: 10.1080/01616412.2019.1588490

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Using either CBS knockdown or the cystathionase (CTH) inhibitor propargylglycine (PAG) to block the TSS pathway significantly increases ferroptosis in tumor cells (98)

3.3 Oxidative stress In MASLD, mitochondria play an important role in metabolism regulation since they modulate oxidation, ATP synthesis and formation of reactive oxygen species (ROS) [27]

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