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As discussed above, GRXs play important but non-overlapping roles in iron trafficking and the biogenesis of iron-containing cofactors (Berndt et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Daiho T, Kanazawa T

Subsequently, colorectal cancer cells release TGF-1 into the tumor microenvironment, where it activates the mothers against decapentaplegic homolog 3 (SMAD3) pathway in memory CD8 + T cells, ultimately impairing their antitumor activity ( LSS is downregulated in tumor cells, leading to intracellular accumulation of 2,3-oxidosqualene

B., Hanania, N., Minard, C

doi:10.1007/s11626-012-9543-7