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doi: 10.1007/s00425-020-03503-1

Ferroptosis, a hot topic of research in recent years, has been gradually enriched by its corresponding regulatory mechanisms

Furthermore, nocturnal application of melatonin has led to an increased myelination and S100 immunoreactivity in crushed sciatic nerves compared to the daily application, whereas there was no difference between both groups in immunoreactivity against the Neurofilament200 protein (Moharrami Kasmaie et al., 2019)

Moreover, a growing body of evidence supports the notion that activating ferroptosis may potently inhibit the growth of HCC cells, thus providing a scientific rationale for targeting ferroptosis as a novel therapeutic strategy for HCC