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Furthermore, the impaired sequestration of mitochondria into autophagosomes in Nix mutant erythroid cells prevents mitochondrial clearance, revealing a crucial function for NIX-mediated mitophagy in the maturation of erythrocytes [150, 151]

Risk factors include occupations requiring prolonged standing, being overweight, having flat feet or high arches, tight calf muscles, and sudden increases in physical activity

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In both in vitro and in vivo studies, the ES2 peptide has shown potent senolytic activity with minimal apoptotic effects on non-senescent cancer cells [128]

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A novel nonpsychotropic cannabinoid, HU-211, in the treatment of experimental pneumococcal meningitis