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In liver tissue from Gclc KO mice, we observed an accumulation of glutamate but no difference in cysteine and glycine levels (Fig
2012) via its orphan G-protein-coupled GPR7 (NPBWR1) and GPR8 (NPBWR2) receptors (Shimomura et al
Often at high doses, targeted cells go through a sequence of cellular degeneration followed by cell death, but at lower doses degenerative changes do not necessarily lead to cell death
