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Description
Several genes have been found to modulate this burst, including a gene encoding the 18-amino acid polypeptide signal systemin and a gene encoding a membrane-bound NADPH oxidase complex (Orozco-Cardenas and Ryan 1999)

however, actually the problem is B 12 deficiency (Selhub et al., 2008)
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Veterin Clin North America Equine Pract

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Hippler FWR, Boaretto RM, Dovis VL, Quaggio JA, Azevedo RA, Mattos-Jr D