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demonstrated that PET NPs (size and dose not reported) can skew the immune balance towards a pro-inflammatory phenotype (shift to Th1/Th17), disrupt immune regulation by decreasing Treg cells and IL-2, and potentially contribute to the development of immune-mediated disorders through increased secretion of pro-inflammatory cytokines and reduced regulatory signalling [87]

Aug 2007;193(2):277-82

Two months with the combined CoQ 10 and creatine supplementation also helped to improve functional performance, body composition, and dyspnea symptoms in patients with the chronic obstructive pulmonary disease [206]

neoformans infection also specifically reduces antibody responses to exogenous cryptococcal polysaccharide, impairing humoral immunity (Goldman et al., 2000)

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