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One hundred healthy bullfrogs and 200 bullfrogs with abnormal fat metabolism were selected to be temporarily reared for 2 weeks before the start of the experiment, during which the bullfrogs were fed basic feed twice a day to acclimatize them to the feed and culture environment

Hepatol Int (2021) 15(2):25882

& Stein, E

The modeled animals should allow the virus to replicate and disseminate to the organs and tissues as in the infected human

10.1016/j.euroneuro.2019.01.105 Eur

The research priorities are clear: Phase I safety trials in healthy volunteers must be completed, followed by Phase II efficacy trials for specific conditions if safety is confirmed