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The DHS-led survival advantage of mice was accompanied by an increase in the total GPx activity as well as mRNA expression levels of seleno-GPxs ( GPx1 , GPx2 , GPx3 , and GPx4 ), reduction of lipid peroxidation, and suppression of inflammatory response (decrease of the expressions of pro-inflammatory genes and infiltration of inflammatory cells) in the radiosensitive organs such as spleen, intestine, and lung

Clin Neuropharmacol 1996, 19: 341348

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Lentz SR

In research models, it is utilized for its ability to reset human gene expression and stimulate the extracellular matrix

Rodents have relatively small lissencephalic brains in which white matter is less than 20% compared to 80% in large animals and humans