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p35 deficiency accelerates HMGB-1-mediated neuronal death in the early stages of an Alzheimers disease mouse model

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2011 Jul;25(7):17821788

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HF: Conceptualization, Supervision, Writing review & editing

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doi: 10.1038/s41569-022-00739-0 40

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Its crucial to consult with healthcare providers for personalized guidance

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Conclusion In summary, HMB provided marked protection against sepsis-induced ALI in the CLP model by reducing histopathological injury, suppressing NF-Bdriven inflammation, alleviating ER stress and apoptosis, and enhancing antioxidant defense via the NRF2/GPX4 pathway

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