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[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Gherasim C., Lofgren M., Banerjee R

Glodowski, D

Applied and environmental microbiology, 74(7), 21712178

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The two extremes of this range are the pro-inflammatory M1 phenotype, associated with active microbial killing, and the M2 phenotype, associated with immune suppression, tissue remodeling and angiogenesis [231]

[146] demonstrated that the regulation of circadian rhythms with melatonin treatment could maintain the anaboliccatabolic balance during OA development, providing a regulatory mechanism linking melatonin to the circadian rhythm and treatment for OA