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135 A Phase 2 trial in patients with ulcerative colitis confirmed the antiinflammatory action of KdPT without any evidence for pigment induction as an adverse effect
Both touch MC4R, but PT-141 is the selective MC4R agent studied for sexual desire, while MT-II binds broadly across MC1R/MC3R/MC4R/MC5R, with pigmentation (MC1R) as its signature
10.1016/j.tem.2013.09.002 105
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Lipolysis of triglyceride-rich lipoproteins, vascular inflammation, and atherosclerosis
