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& Seumatsu, Y
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By interacting with reactive oxygen species, curcumin may activate apoptotic pathways

[DOI] [PubMed] [Google Scholar] 144.Sambon M., Wins P., Bettendorff L

Clinical and molecular characterization of early-onset colorectal cancer

When GSH, the naturally more abundant form, encounters free radicalsincluding singlet oxygen, hydroxyl radicals, and superoxide radicals, all of which have the potential to damage cells and tissuesit can be oxidized to GSSG
Data from the Minnesota Green Tea Trial showed a 6.7% incidence of ALT elevation in postmenopausal women consuming 843 mg/day EGCG, with polymorphisms in the COMT and UGT1A4 genes contributing to interindividual variability in toxicity (245)
