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[DOI] [PubMed] [Google Scholar] 12.Webb A.R., DeCosta B.R., Holick M.F

The resulting products, generally termed advanced oxidation protein products (AOPPs), have, therefore, been acknowledged as in vivo markers of chronic inflammation [23]

[DOI] [PubMed] [Google Scholar] Paul D

(2025) reported that microglia exhibit region-specific increases and morphological alterations in response to combined MIA and repeated SDS stress (a two-hit mouse model, 2HIT)

The metabolism of PAHs, such as benzo[a]pyrene, predominantly relies on GSTs, which conjugate the highly carcinogenic epoxides with glutathione, producing water-soluble metabolites that are excreted via bile or urine, thereby reducing accumulation in target organs and the risk of DNA damage (Moorthy et al., 2015

Typically, low levels of ROS are associated with the maintenance of stem cell and self-renewal capacity, whereas elevated ROS levels can drive differentiation or induce cellular senescence