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Description
Under cystine starvation, the GCN2-eIF2-ATF4 pathway is activated, leading to an upregulation of CHAC1 expression
The largest published trial (METAOD006/OPTIONS) randomized 502 adults with obesity to AOD-9604 or placebo for 24 weeks alongside a diet and exercise program

[Free Fulltext PMC] 2824

USA 40 , 10801087 (1954)

B., Lindsay, R
The Gerontologist, 55 (6), 901
