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Safety Monitoring and Adverse Event Profiles Tirzepatide's adverse event profile is well-characterized from large-scale Phase 3 trials

IM Shots are injected into the muscle (usually the arm or glute), creating a depot of nutrients that absorbs gradually over time

The most commonly observed side effects are gastrointestinal in nature, primarily related to tirzepatides effects on gastric emptying and incretin receptor activation

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It is recommended for travellers visiting rural or forested areas where exposure to ticks is more likely

Treatment regimens and guidance: The British National Formulary (BNF) and NICE Clinical Knowledge Summaries outline treatment regimens for B12 deficiency