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Meth-Cohn, Eds., Comprehensive Natural Products Chemistry

Regulatory history: Sermorelin was FDA-approved in 1997 under the brand name Geref for the treatment of growth hormone deficiency in children

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NAD + is mainly consumed in three ways, in which NA is produced, and 4 enzymes, sirtuins, ADP-ribosyl transferases (ARTs), poly-ADP-polymerases (PARPs), and cADP-ribose synthases, are involved (Figure 1)
