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Based on a previous study, the following compounds have been found as GPx4 activator: lapatinib, ferrostatin, liproxstatin-1, and PKUMDL-LDL-102 (Fig

Herxheimer A, Petrie KJ

Even though the effect of taurine on protein phosphorylation remains to be stablished, enough experimental evidence has been obtained to suggest that taurine loss induces the reduction of SR Ca2+ATPase activity and the phosphorylation state of phospholamban, which is accompanied by delayed myocardial relaxation and ROS accumulation (46,76,165)

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