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With the current absence of technologies to rectify the actual mutations that underlie mitochondrial diseases, medical science can only address the resulting oxidative stress as a potential therapeutic option

However, the parenteral route of administration has several drawbacks, since it is invasive, painful, and poorly accepted by patients, especially when prolonged or repeated use is required [5]

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Ferroptosis was coined by Stockwell et al

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In addition, there is a U-shaped association between selenium exposure and some diseases, such as type 2 diabetes and fractures [117]