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The evidence outlined in the Sections Unlocking Melatonins Anti-Amyloidogenic Potential and Melatonins Neuroprotective Mechanisms against A toxicity indicates that melatonin exhibits anti-amyloidogenic properties and mitigates the neurotoxic effects of Aos, thereby potentially reducing the risk of developing AD or slowing its progression

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Consistent with the compartmentalization model, local axonal damage can be ameliorated by reducing oxidative damage, targeting the dual leucine zipper kinase (DLK) enzyme and potentially with exercise

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[DOI] [PMC free article] [PubMed] [Google Scholar] [5].Walsh DM, Hartley DM, Condron MM, Selkoe DJ, Teplow DB