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[DOI] [PubMed] [Google Scholar] 364.Lee Y.R., Noh E.M., Han J.H., Kim J.M., Hwang B.M., Kim B.S., Lee S.H., Jung S.H., Youn H.J., Chung E.Y., et al
It leads to inconsistent data, failed experiments, and results that can't be replicated
This interaction inhibits Keap1-mediated ubiquitination and degradation of NRF2, resulting in the upregulation of antioxidant genes and contributing to chemotherapy resistance in NSCLC [100]
The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation
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