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Description
It drives the transition from proliferation to differentiation and increases the number and length of multinucleated myotubes in a dosedependent manner.The mechanism is mainly related to NNMT inhibition, restored NAD levels, and activation of the SIRT1PGC1 pathway

Studies suggest that lowering NNMT levels may help counteract some of the mechanisms underlying impaired stem cell function in these disorders

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Participants were followed up over a period of 90 days

doi: 10.1111/j.1472-8206.2009.00667.x

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