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Collectively, these symptoms associated with acute mountain sickness are related to harsh environmental factors such as low oxygen, cold, and ultraviolet rays (Askew, 2013)

Multiple signaling pathways regulate contractile activity-mediated PGC-1 gene expression and activity in skeletal muscle cells

Cochrane Database Syst Rev 4;7(7):CD009770

Oxidative stress is caused by a variety of environmental and dietary factors such as consumption of bad oils, psychological stress, environmental toxins (think mold, air pollution, pesticides), and others

doi: 10.1016/j.envres.2014.09.005

Identification of glial cell population Glial cells are non-neuronal support cells that are present in most complex nervous systems but whose evolutionary origin and homology remain unclear 56