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Even though GSH levels were below the threshold for rescuing WT cell growth in cystine-free conditions, co-culturing with GGT1 + cells led to complete rescue of WT cell growth (Fig

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Given the significant role that UPS plays in the development of renal disorders, many renal therapies targeting UPS have also been found to have good potential for application, such as proteasome inhibitors, represented by bortezomib

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