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They used an app1 strain (with no differences in capsule size, melanin formation, or growth at 30 or 37C) that was more easily ingested by macrophages even in immunocompetent mice that were deficient for complement C5

More papers with interventions of curcumin and glutathione are needed to deduce its efficacy in a large pool of patients

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It also increases aquaporin-4 (AQP-4) involved in glial edema (28, 47), and poli ADP-ribose polymerase-1 (PARP-1) that favors necrosis through glial activation (28)
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