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Clin Interv Aging, 2008

(2016) 113(44):E6806E12

GHK-Cu works through copper delivery to metalloenzymes and broad gene expression modulation, affecting not only collagen synthesis but also collagen cross-linking (via lysyl oxidase), glycosaminoglycan production, anti-inflammatory pathways, and antioxidant defense systems

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Moreover, these aberrant disulfide bonds have also been identified in vivo (Karch et al., 2009
