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We therefore extracted gene expression values for all GSTs present in our neuronal transcriptome (Supplementary Table S5) and found that other GSTs, such as GSTM1 and GSTM3, are markedly less expressed in neurons of the hooded seal than in mice, which caused the overall GST expression to be similar between the species

In addition, the altered structure of the DNA makes it unrecognisable by DNA-damage-repair proteins

L.CoutoC

Cruzat V., Macedo Rogero M., Noel Keane K., Curi R., Newsholme P., 2018

The canonical pyroptosis pathway is initiated by the activation of the NLRP3 inflammasome complex, which includes NLRP3, the adaptor protein ASC containing the CARD domain, and pro-caspase-1 [65]

The level of homocysteine depends on the amount that is formed in the conversion of SAMe and SAH (S-adenosyl homocysteine) and the amount that is recycled or further broken down
