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PngCWLindnSKGilshenanKSZoetendalEGMcSweeneyCSSlyLIet al

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Crystal structures indicate that the His-51 deprotonates the nicotinamide ribose, which deprotonates Ser-48

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For example, nisin inhibits the proliferation of cancer cells by the formation of ion channels on the cell membrane, releasing lactate dehydrogenase, increasing the number of reactive oxygen species, and obstructing the mitochondrial respiration of cancer cells

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Here, GGT knockout mutant was shown to produce an increased amount of medium-sized PGA fragments (1 10 5 Da) as compared to the wild-type strain, in which both the amount and the size of PGA fragments (5 10 3 Da) decreased considerably

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