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For example, Bifidobacterium pseudocatenulatum increases SBAs such as LCA and DCA, suppressing Th1/Th17 responses (79), while ginsenoside Rk3 reduces IL-17 production by shifting BA profilesan effect primarily observed on ILC3s, another IL-17 source (80)

Abstract Cells use transcription-coupled nucleotide excision repair (TC-NER) to efficiently resolve transcription-blocking DNA lesions caused by genotoxic stress such as ultraviolet (UV) irradiation

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PARP inhibition in cancer: an update on clinical development