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Low-dose naltrexone has shown beneficial effects when compared against a placebo after 12 weeks of treatment, with a mean difference of 0.34 on a 110 pain scale [45]

We fed a culture of gut microbes with l-carnitine and measured the TMA that the microbes produced

J., Haidar, M., Kooij, G

As depression has been previously shown to be associated with changes in neurometabolites, mood and anxiety ratings were performed: the Beck Depression Inventory II (BDI-II) [30] for mood, the Spielberger State Anxiety Inventory (STAI) for anxiety [31]

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The myocardium has the highest carnitine concentration of any tissue, reflecting its dependence on fatty acid oxidation