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PMID: 39884044 Cancer Lett 2025 Oct 2:218073

In a double-blind, placebo-controlled, randomized clinical trial, it was shown that after 12 months of treatment, vitamin E administration did not influence survival and motor function in ALS

Fisher SP, Sugden D

This therapy involves the administration of the local anesthetic procaine via an intravenous route, leading to a range of positive outcomes for individuals who undergo the treatment

:Basic cofactors consist of: Vitamins A and Vitamin D (11,000 IU and 3000 5000 IU respectively) Vitamin C at 4000+ mg per day Vitamin E B vitamin complex with P5P, biotin and pantethine (without including cyano B12 or folic acid) A 1:1 magnesium:calcium supplement Zinc, 50 mg per day Omega 3 fatty acids, 2-6 caps per day Optional Basic Cofactors include: Glycophospholipids Additional pantethine Multimineral supplements (choline, selenium) Alpha lipoic acid D-Ribose CoQ-10 Titrate B12s while adjusting methylfolate and potassium Methylcobalamin (MeB12) should start at 15-20 mg per day Adenosylcobalamin (AdoB12) should start at 10 mg per week Titrate methylfolate to sufficiency, starting at 1 mg Titrate L-carnitine fumarate (LCF) to effectiveness, starting at 125 mg per day and aiming for 500-1000 mg per day, stopping when an increase of 250 mg makes no difference

All of these act as UPR receptors