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Such interventions may restore metabolic balance in neurons, potentially slowing disease progression by improving energy production and reducing oxidative stress (Ashrafi and Ryan, 2017)

Interestingly, ursodeoxycholic acid, the only treatment approved by the Food and Drug Administration for the treatment of primary biliary cirrhosis, a chronic cholestatic disorder, was shown to prevent the fall in GCL expression during chronic cholestasis (Serviddio et al., 2004) and increase GCL expression in cultured rat hepatocytes (Mitsuyoshi et al., 1999)

It consists of the papillary dermis, with a loose collagen network, and the reticular dermis, characterized by dense connective tissue

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Looking at these markers together gives you a powerful, personalised roadmap