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96 The major endogenous nonenzymatic low-molecular-mass antioxidants include N-acetylcysteine, glutathione, uric acid, melatonin, coenzyme Q and others

Our findings are the first to demonstrate that GCLC desuccinylation mediated by SIRT2 directly regulates the rapid activation of GCLC upon oxidative stress, which provides a promising adjunct therapeutic target for cancer treatment

Certain strategies have been shown to treat symptoms associated with defective mitochondria

It may also be able to help with muscle repair after exercise or injury

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