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In contrast, mutations in the PKC phosphorylation sites in the C-tail gave rise to PKC-site mutants, which demonstrated partial impairment in sequestration and endocytosis but completely diminished downregulation, indicating an important role for PKC in this process (Prinster, 2003)

"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age

Meaningful structural improvements in bone continuity and strength have been observed between weeks four and eight in animal models
