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Inhibition of RNA polymerase III transcription by Triptolide attenuates colorectal tumorigenesis

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Further definition of these types of inclusions in animals is required, and their pathogenetic significance is not understood

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that AFB1, as the parent compound, inhibited rat liver mitochondrial electron transport at the antimycin A-sensitive site (10) and postulated subsequently (5) that the enhanced liver cell necrosis and acute toxicity observed in the low-protein animals could be due to the low rate of metabolism and clearance of AFB1 with a consequent effect on mitochondrial respiration

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