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doi: 10.1039/b103471p

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The PINK1/Parkin pathway governs mitophagy: mitochondrial membrane potential (m) collapse stabilizes PINK1 on the outer membrane, phosphorylating ubiquitin to recruit Parkin, which ubiquitinates mitochondrial proteins (e.g., Voltage-Dependent Anion Channel 1 (VDAC1)) for autophagic degradation [159]
Therefore, inhibition of IGFBP7 and PRDX3 represents a potential novel therapeutic target
doi: 10.1016/j.lwt.2020.110035 56 KajlaP.SharmaA.SoodD
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