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Further external validation in a larger population is necessary to confirm this finding

To do this, we first scanned predicted coding sequences for the presence of the ParB-like nuclease domain (PF02195

C.HuangH

Mitochondrial-driven apoptosis can occur through the intrinsic (mitochondrial) or extrinsic (cell death receptor) pathways, although the extrinsic pathway requires the intrinsic pathway for amplification of the death signal (Martini and Passos, 2023)

J Intern Med 242:465478 Wallimann T, Wyss M, Brdiczka D et al (1992) Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: thephosphocreatine circuitfor cellular energy homeostasis