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doi: 10.1155/2021/2270472 29 BasheerM
Aside from its role in catecholamine catabolism, COMT converts an antiestrogen compound (2-hydroxyestradiol) to a proestrogen (2-methoxyestradiol) and leads to an estrogen-rich environment
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1a) and plasma alanine aminotransferase (ALT) levels (Fig
The review outlines the classification of commonly used anabolicandrogenic compounds, discusses their pharmacological mechanisms of action, and integrates clinical, experimental, and epidemiological data on associated adverse outcomes
