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The body absorbs vitamin B12 with the help of intrinsic factor, made in the stomach

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However, systemic anti-aging claims remain largely Level D (Pre-clinical)

Introduction Vitamin B12 (cobalamin) deficiency can affect several organs, such as the bone marrow and the peripheral and central nervous systems [1]

Kisspeptin is the notable exception, dosed at 1 to 10 mcg/kg in clinical research

Wrinkle reduction: Badenhorst et al