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Koeth RA, Levison BS, Culley MK, Buffa JA, Wang Z, Gregory JC, et al

Peer review Peer review information Nature Reviews Drug Discovery thanks the anonymous reviewers for their contribution to the peer review of this work

Through its targeted action, MOTS-c helps support hormonal balance, particularly in regulating the metabolism of insulin and leptin, the key hormones responsible for hunger, satiety, and energy usage

Store below 25C in a cool, dry place away from direct sunlight

Stearic acid does not contribute to low-density lipoprotein (LDL) cholesterol, the unhealthy cholesterol

Cells were fixed and permeabilized in 4% paraformaldehyde with 0.5% Triton-X 100 in PBS for 10 minutes