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doi: 10.1016/j.diabres.2014.09.058

Ocular studies further suggest REV-ERB agonism protects retinal neurons from oxidative stress, potentially delaying photoreceptor degeneration in retinopathies (Huang et al., 2022b)

MicroRNAs MicroRNAs (miR) are non-coding, single-stranded, 1725 nucleotide-long RNA fragments that regulate biological processes such as proliferation, invasion, metabolism, apoptosis, and autophagy through post transcriptional gene silencing [432]

Collectively, this work proposes an LDH-based strategy that concurrently alleviates pathological acidosis, oxidative stress, mitochondrial dysfunction, and macrophage polarization imbalance, providing a potential nanotherapeutic approach for OA management

A detailed schematic representation is shown for the immunization experiment

Antonie Van Leeuwenhoek 96, 115139