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Acta Neuropathol 115: 193203, 2008 [DOI] [PubMed] [Google Scholar] 29.Burke WJ, Li SW, Williams EA, Nonneman R, Zahm DS

Our results showed a 10-week chronic ethanol exposure in all four drinking paradigms was sufficient to cause significant cognitive behavioral impairments in both WT and APP/PS1 mice during NOR, Y-maze, and MWM tests

Thus, unlike single-treatment, which may only very partially depict possible NO-system involvement, BPC 157, known to induce NO-release by itself [98,99], is always investigated under the condition of the triple regimen, and may equally overwhelm the adverse effects of L-NAME, L-arginine, and their combination as well [97]