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According to the World Obesity Atlas 2022, it is predicted that by 2030, one out of every three women and one out of every seven men will be classified as obese (Chand et al., 2024)

206 Chen et al

PMID: 50 Domagala-KulawikJKwiecienIPankowskiJPasieka-LisMWoloszDZielinskiM

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Appetite signals can begin, but measurable weight change in the first week was not a documented trial outcome

Diets high in 6 polyunsaturated fatty acids (e.g., linoleic and arachidonic acid found in oils) enrich adipocyte membranes with precursors for pro-inflammatory eicosanoids (for instance, PGE 2 from arachidonate), which yield signals activating ERK/PI3K pathways 364