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Studies in mice showed that colistin toxicity is associated with the activation of (i) the mitochondrial apoptotic pathway, (ii) the death receptor pathway, and (iii) the endoplasmic reticulum pathway 20,21

E.Van De WaterJ

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[DOI] [PubMed] [Google Scholar] 190.Chen C, Krausz KW, Shah YM, Idle JR, Gonzalez FJ

12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance

Gwinn DM, Shackelford DB, Egan DF, Mihaylova MM, Mery A, Vasquez DS, et al
