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the majority of these enzymes are heme protein mono-oxygenases of the cytochrome P450 class

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J Cell Mol Med 25:960974 Yiu WH, Li RX, Wong DWL, Wu HJ, Chan KW, Chan LYY, Leung JCK, Lai KN, Sacks SH, Zhou W, Tang SCW (2018) Complement C5a inhibition moderates lipid metabolism and reduces tubulointerstitial fibrosis in diabetic nephropathy