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Furthermore, PET imaging in a disseminated mouse model demonstrated tumor cell localization in femur, tibia and spine, highlighting the potential of this antibody-based PET radiopharmaceutical for non-invasive CD38-positive myeloma imaging [101]

E., & Butyugov, A

But the mechanism is well-characterized and the target (NNMT in adipose tissue) is a legitimate pathway for visceral fat reduction

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In particular, immune modulatory effects of anti-CD38 antibodies during cancer therapy may be at least in part related to the decrease in CD38 NADase activity