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developed a novel reactive matrix, ( E )-2-cyano- N -(2-(2,5-dioxo-2,5-dihydro-1 H -pyrrol-1-yl)ethyl)-3-(4-hydroxyphenyl)acrylamide (CHC-Mal), for the selective detection of free thiol groups in metabolites and proteins by MALDI-MS

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Lack of natural folate and SAMe also means lack of added methyl groups, which may result in various health conditions including neurological disorders

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Dixon et al., 2007)

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Reads were counted with HTSeq (v0.11.0)

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Cluster 11 contains 7 nodes and 9 edges with a score of 3.000, seeded by the node AKT1

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