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Neuron 55 , 377391 (2007)

Evidence have shown that the process of metabolic reprogramming can be regulated by the underlying genetic factors that drive tumorigenesis

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Most episodes last approximately seven to 10 days

Patients with insufficient glutathione stores (e.g., alcoholics and acquired immunodeficiency syndrome patients) and patients with induced cytochrome P-450 enzymatic activity (e.g., alcoholics and those taking concurrent anticonvulsant or antituberculous medications) may be at greater risk for developing acetaminophen-induced hepatotoxicity following overdose (as opposed to therapeutic dosing described earlier)

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