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In this combined analysis, we observe that the degree of BMI loss depends strongly on sex, drug type, time on treatment and drug dosage, consistent with previous reports 11 , and has a relatively weak dependence on pre-treatment BMI (with higher starting BMI associated with greater BMI loss)

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Extracellular glutathione S-transferase omega-1, a cytosolic enzyme that modulates the S-thiolation status of intracellular factors involved in the inflammatory response, and its polymorphisms have been associated with an increased risk to develop COPD and could have a biological and clinical significance in cystic fibrosis (115)

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